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5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Skin has specialized touch receptors that can tell different sensations apart.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Imiquimod 5% cream reduced equine sarcoids in most cases.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The HR protein's role as a repressor is essential for controlling hair growth.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Tiny needles with valproic acid can effectively regrow hair.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Wnt signaling is crucial for skin wound healing and reducing scars.

Inactive hair follicle stem cells help prevent skin cancer.

Dermoscopy improves diagnosis and treatment monitoring for children's skin infections, inflammations, and hair disorders.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

The most common skin problems in Indian children are infections and eczemas.