45 citations,
April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
44 citations,
September 2014 in “Cell Death & Differentiation” Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
44 citations,
January 2007 in “Biological & pharmaceutical bulletin” Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.
43 citations,
November 2019 in “American Journal of Clinical Dermatology” FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.
42 citations,
June 2020 in “Seminars in Oncology” Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
42 citations,
April 2011 in “European Journal of Dermatology” Early balding men may have insulin resistance, but lifestyle changes can help.
39 citations,
August 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
38 citations,
September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
37 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
37 citations,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
37 citations,
April 2008 in “The Cochrane library” 5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.
36 citations,
January 2014 in “Evidence-based Complementary and Alternative Medicine” Pumpkin seed oil helps hair growth in men with hair loss.
36 citations,
January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
34 citations,
October 2018 in “Journal of The American Academy of Dermatology” Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
34 citations,
June 2010 in “Archives of Disease in Childhood” Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.
34 citations,
March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
32 citations,
February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
32 citations,
May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
32 citations,
January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
30 citations,
September 2017 in “Clinics in Dermatology” Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
30 citations,
April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
29 citations,
February 2018 in “Genetics research international” Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
29 citations,
January 2011 in “Journal of Obstetrics and Gynaecology” Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
28 citations,
October 2018 in “Clinical Obstetrics and Gynecology” Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
28 citations,
August 2014 in “Journal of Assisted Reproduction and Genetics” The VEGF +405G allele may increase the risk of PCOS in South Indian women.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
26 citations,
January 1994 in “Hormone and Metabolic Research” Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
25 citations,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
25 citations,
December 2008 in “The Journal of Urology” Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.
25 citations,
November 2001 in “Kidney International” Male hormones worsen kidney transplant damage, but blocking them helps.