research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
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research Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice
Dutasteride works better than finasteride for preventing and treating prostate cancer.
research Ovarian Hilus-Cell Hyperplasia and High Serum Testosterone in a Patient With Postmenopausal Virilization
A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.
research Solitary Pedunculated Multicystic Viral Plaque Associated with Canine Papillomavirus 18 in a British Bulldog
A British Bulldog had a unique viral plaque caused by Canine papillomavirus 18, different from typical tumors.
research Multiple Follicular Abnormalities in a 1-Year-Old Cat Consistent with Basaloid Follicular Hamartomas
A one-year-old cat had multiple benign skin tumors similar to those known in humans.
research Long-Term Management with Adipose Tissue-Derived Mesenchymal Stem Cells and Conventional Treatment in a Dog with Hepatocutaneous Syndrome
Combining amino acid and stem cell therapy may help manage hepatocutaneous syndrome in dogs.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Efficacy and Safety Evaluations of Topical Proretinal Nanoparticles
Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
research Is Dehydroepiandrosterone a Hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research The Evaluation and Treatment of Androgen Excess
High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.
research Signaling Pathways and Targeted Therapeutic Strategies for Polycystic Ovary Syndrome
Effective PCOS treatments require targeting specific signaling pathways.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Primary Hypothyroidism and Thyroid Goiter in an Adult Cat
The cat's hypothyroidism was successfully managed with levothyroxine, leading to a stable condition.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors
Inactive hair follicle stem cells help prevent skin cancer.
research Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research The Case of the Elusive Androgen
The patient's high testosterone was reduced by a medication that suppresses gonadotropin.
research Potential Pharmacological Activities of Pumpkin Seeds as a Functional Food: A Comprehensive Review
Pumpkin seeds may improve health due to their rich nutrients and potential to treat various conditions.
research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
research Edible Seeds From Cucurbitaceae Family as Potential Functional Foods: Immense Promises, Few Concerns
Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.
research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Harlequin Ichthyosis (ICHQ): A Juvenile Lethal Mouse Mutation with Ichthyosiform Dermatitis
The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
research Oral Itraconazole for the Treatment of Giant Tufted Angioma with Hair Loss Arising During Pregnancy: A Case Report
Itraconazole effectively treated a woman's painful skin condition and hair loss.
research Birt-Hogg-Dubé Syndrome: Genetic and Clinical Insights
Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.
research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue
KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.
research In Vivo Imaging of Mammary Epithelial Cell Dynamics in Response to Lineage-Biased Wnt/β-Catenin Activation
Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.