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GlossaryEnamel Hypoplasia

developmental condition where tooth enamel is thin or deficient

Enamel Hypoplasia is a developmental condition where the enamel, the hard outer layer of the teeth, is thinner or deficient due to disruptions during tooth formation. This can result in pits, grooves, or even missing sections of enamel, making the teeth more susceptible to decay and sensitivity. Causes can include nutritional deficiencies, illness, or genetic factors.

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research Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organs

22 citations, July 2020 in “iScience”

Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.

research Focal Dermal Hypoplasia Associated With Lymphedema: A Case Report From Saudi Arabia

April 2023 in “Curēus”

A 12-year-old girl in Saudi Arabia with Focal dermal hypoplasia showed skin and dental symptoms, highlighting the condition's variability and the need for personalized treatment.

research Evaluation of Clinical and Oral Findings in Patients With Epidermolysis Bullosa

1 citations, June 2023 in “Medicina”

People with Epidermolysis bullosa have many health problems including poor oral health, which is often neglected due to other medical issues.

research Over-Expression of Thymosin Beta4 Promotes Abnormal Tooth Development and Stimulation of Hair Growth

34 citations, December 2009 in “The International Journal of Developmental Biology”

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

research Read-Through for Nonsense Mutations in Type XVII Collagen-Deficient Junctional Epidermolysis Bullosa

5 citations, April 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new therapy for a skin blistering condition has not been developed yet.

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