Oral Itraconazole for the Treatment of Giant Tufted Angioma with Hair Loss Arising During Pregnancy: A Case Report

    November 2019 in “ Journal of dermatology
    Wei Wu, Jianqiang Shi, Zhaojun Li, Li Ding, Shuhui Dou, Sushmita Pradhan, Xin Ran, Yuping Ran
    Studysummary This case report details the successful use of oral itraconazole in treating a giant tufted angioma with hair loss that developed during pregnancy, leading to significant symptom relief and hair regrowth after discontinuation of the medication. Our plain-language summary of this paper — not a Tressless recommendation.
    A 35-year-old Chinese woman developed a giant tufted angioma with severe pain and hair loss during her pregnancy. After giving birth, she was treated with oral itraconazole (200 mg twice daily), which significantly relieved her pain within 3 days and led to hair regrowth after 1 month. The treatment was discontinued after 3 months, and sustained clinical improvement was observed 6 months post-treatment. The case highlighted the potential of itraconazole, an antifungal drug, as a well-tolerated treatment option for large and painful tufted angiomas, especially given its fewer side effects compared to other systemic treatments.
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