15 citations
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January 2013 in “European Journal of Pediatrics” Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.
April 2020 in “Journal of the Endocrine Society” This case report emphasizes the importance of recognizing non-classic congenital adrenal hyperplasia as a cause of hyperandrogenism and the need for genetic counseling given potential familial implications.
63 citations
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January 2012 in “The European Journal of Contraception & Reproductive Health Care” This study concluded that combined hormonal contraceptives containing desogestrel, drospirenone, or cyproterone acetate were associated with a higher risk of venous thromboembolism compared to those containing levonorgestrel.
16 citations
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January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
2 citations
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May 2017 in “Maturitas” Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
December 2024 in “Quality in Sport” This review discusses immunological abnormalities in PCOS, focusing on inflammation and autoantibody production, and reports no new results; it suggests exploring new therapeutic drug targets.
January 2020 in “Medical journal of Dr. D.Y. Patil Vidyapeeth” This study found that polycystic ovarian syndrome (PCOS) is the most common cause of cutaneous manifestations of hyperandrogenism in women of reproductive age, with hirsutism severity correlated to serum testosterone levels.
1 citations
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January 2018 in “Journal of Gynecologic Surgery” This article reports two cases where ovarian hyperthecosis caused hyperandrogenism in postmenopausal women, confirmed by imaging and resolved after bilateral oophorectomy.
1 citations
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November 2025 in “Wiener Medizinische Wochenschrift” This study reports a case of fatal HHV-6 encephalitis and vasculitis in a previously healthy 49-year-old male, highlighting the occurrence of this condition even in individuals without typical risk factors, such as immunocompromised status.
1 citations
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June 2023 in “Dermatology and therapy” This study found that patients with alopecia areata had a higher incidence rate of herpes simplex infection compared to matched individuals without the condition.
11 citations
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September 1990 in “Clinical Endocrinology” This study found that girls with prepubertal simple hypertrichosis had significantly higher plasma levels of dihydrotestosterone compared to controls, which does not align with other androgen markers and warrants further investigation.
1 citations
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October 2023 in “European Journal of Dermatology” This study found that combining hair transplantation with platelet-rich plasma injections was more effective than hair transplantation alone for improving hair loss in patients with androgenic alopecia.
12 citations
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June 2006 in “Pediatric blood & cancer” This case report describes a 16-year-old male with pernicious anemia, autoimmune hemolytic anemia, and alopecia areata, highlighting the delayed diagnosis of the hemolytic anemia when cobalamin therapy failed to improve anemia symptoms.
2 citations
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September 2004 in “Fertility and sterility” This review discusses the cosmetic and health implications of hirsutism and highlights its potential link to serious underlying disorders, but it presents no new clinical findings.
May 2017 in “Journal of the American Academy of Dermatology” January 2025 in “Indian Journal of Biochemistry and Biophysics” This study found that the uric acid to creatinine ratio had excellent diagnostic ability for polycystic ovary syndrome, with significant associations to metabolic and hematologic changes in PCOS patients.
July 2007 in “Hair transplant forum international” This article discusses advancements in hair transplant procedures that allow for more follicular units to be transplanted per session but notes the lengthy procedure time required.
24 citations
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May 1985 in “The Journal of Clinical Endocrinology & Metabolism” In this case study, the authors identified a circulating low molecular weight inhibitor that may contribute to insulin resistance in a woman with acanthosis nigricans and polycystic ovary syndrome.
4 citations
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January 2015 in “Case reports in urology” This paper presents a case of penile tourniquet syndrome in an 8-year-old boy caused by his mother's hair coil, highlighting its rarity beyond infancy.
January 2009 in “UWA Profiles and Research Repository (University of Western Australia)” This study found that the metabolic syndrome is significantly more prevalent in women with polycystic ovary syndrome compared to controls, highlighting an association between PCOS and increased cardiometabolic risk.
4 citations
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April 2019 in “Gynecological Endocrinology” This study found that the rs 1570360 polymorphism and the T-G-C haplotype of the VEGF gene may be associated with a protective factor against polycystic ovary syndrome in a Brazilian population.
52 citations
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November 2009 in “International journal of gynaecology and obstetrics” This study found that hyperandrogenemia in Chinese women with PCOS is associated with higher risks of type 2 diabetes and obesity, suggesting it should be prioritized in managing PCOS-related infertility.
8 citations
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February 2022 in “Vascular Health and Risk Management” This review highlights the increased cardiovascular risk associated with certain dermatologic diseases like psoriasis and hidradenitis suppurativa but reports no new clinical findings.
January 2026 in “Advances in Dermatology and Allergology” In this study, researchers observed that patients with alopecia areata showed higher capillary density and signs of neovascularization compared to controls, suggesting a potential link between alopecia areata and microcirculatory changes.
June 2026 in “kerbala journal of pharmaceutical sciences” In this case-control study, individuals with alopecia areata showed significantly elevated levels of inflammatory markers IL-4, IFN-γ, and CRP, as well as reduced serum Folate and Ferritin, suggesting the condition's multifactorial pathophysiology involves immune activation, systemic inflammation, and micronutrient deficiencies.
December 2015 in “Vascular Pharmacology” Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
December 2022 in “Biomedicine” This study found that men with early onset androgenetic alopecia often have higher serum uric acid levels and an increased prevalence of hyperuricemia compared to controls.
7 citations
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October 2020 in “Journal of The American Academy of Dermatology” This systematic review and meta-analysis found that hidradenitis suppurativa is associated with an increased risk of major adverse cardiac events, including cerebrovascular accidents and myocardial infarction, although study heterogeneity affects the magnitude of risk.
19 citations
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April 2018 in “Clinical cardiology” This study found that among older men, low levels of free dihydrotestosterone were associated with an increased risk of developing atrial fibrillation.
16 citations
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January 2012 in “European Journal of Endocrinology” This study reports an increased frequency of the DI genotype of the ACE gene polymorphism among women with PCOS, notably in those with hyperandrogenism, and an association of the II genotype with insulin resistance.