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Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.

A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.

Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.

Hyperthyroidism can hide signs of high androgen levels in females.

Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Polymeric nanoparticles show promise for treating skin diseases.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Fat cells help recruit healing cells and build skin structure during wound healing.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

PGD2 stops hair growth and is higher in bald men with AGA.

Sebocytes play a key role in controlling androgen levels in human skin.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.