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In this study, the researchers reported that patient impacts and symptoms of hidradenitis suppurativa, as assessed by HSIA and HSSA measures, are associated with clinical characteristics such as the number of abscesses and inflammatory nodules.

This article reviews the pathophysiology of hidradenitis suppurativa and suggests that a complex interplay of genetic, immunological, and biomechanical factors contributes to the condition, but presents no new clinical findings.

This study found that mechanical stress activates a WISP-1/Hedgehog signaling axis that contributes to ligamentum flavum hypertrophy and fibrosis, identifying Hedgehog signaling as a potential therapeutic target.

In this study, researchers found that transgenic expression of the Hairless gene in keratinocytes can restore hair follicle regeneration in Hr-deficient mice by repressing Wise, a modulator of Wnt signaling.

This review discusses the characteristics, complications, and treatment options for hidradenitis suppurativa, a chronic skin disorder with systemic effects, without presenting new clinical findings.

This review discusses recent advancements in Wound Induced Hair Neogenesis in mice, emphasizing the potential of neogenic hair regeneration to enhance understanding of adult mammalian regeneration, but reports no new experimental results.

Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.

This review examines the role of Hairless, a nuclear receptor corepressor, in regulating Wnt signaling during hair cycling and reports no new clinical results.

A 4-year-old girl had a rare hair disorder affecting only part of her scalp.

This study identified a novel locus for hereditary hypotrichosis simplex on chromosome 13q12.12~12.3 in a four-generation Chinese family.

This article discusses the pathogenesis of hidradenitis suppurativa, highlighting follicular occlusion and inflammation as key factors in disease development, but reports no new clinical results.

This article discusses the challenges in diagnosing and treating hidradenitis suppurativa, a recurrent skin disease, noting the lack of effective treatments and the need for more research, but it reports no new findings.

In this report, a 16-year-old Saudi girl with Woodhouse-Sakati Syndrome exhibited unique findings, including hepatic hemangioma and low growth hormone, suggesting the importance of considering WSS in similar clinical presentations.

This study identified a novel splice site mutation in the LIPH gene associated with autosomal recessive woolly hair, contributing to understanding the genetic basis of this condition.

This review discusses the importance of early diagnosis and the management of hidradenitis suppurativa, reporting no new clinical results but highlighting current therapeutic approaches and need for collaboration in treatment.

This case report describes the first known association of hypertrichosis lanuginosa acquisita with autoimmune hepatitis, expanding the list of conditions linked to this rare disorder.

This study found that SHJH hr mice, with a Hairless gene mutation, exhibit accelerated skin aging potentially due to poor antioxidative protection, highlighting the Hr gene's role in skin aging.

This case report describes regression of hidradenitis suppurativa lesions in two patients after 16 weeks of adalimumab treatment.

This review explores the inflammatory pathogenesis and clinical presentation of hidradenitis suppurativa, highlighting the complexity of treatment and the impact on patients' quality of life, while also examining emerging therapeutic options.

In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.

This review presents an evidence-based algorithm for managing hidradenitis suppurativa in primary care, highlighting the need for more research on treatment effectiveness and the disease's pathogenesis.

This study found that laser hair removal effectively reduces disease severity in hidradenitis suppurativa with minimal side effects, likely due to the destruction of hair follicle units.

This study found that using an ultrasound hollow microneedle array enhanced transdermal delivery of finasteride, accelerating hair regrowth in mice with androgenetic alopecia compared to other delivery methods.

This review discusses genetic mutations associated with Hutchinson-Gilford progeria syndrome and reports no clinical results; the authors emphasize the importance of cardiovascular monitoring in management.

This study observed that some patients with homozygous c.736T>A mutation in LIPH may have mild hypotrichosis with long hairs in adulthood.

This article presents an overview of uncombable hair syndrome, emphasizing its clinical and molecular characteristics and noting systemic manifestations such as neuropsychiatric, ophthalmic, and cardiopulmonary issues.

In this study, a comprehensive treatment approach involving multiple therapies was found to play a crucial role in managing hidradenitis suppurativa in patients with intellectual and developmental disorders despite practical challenges.

This study found that WISP-1 plays a key role in ligamentum flavum fibrosis through the Hedgehog-Gli1 pathway, with cyclopamine showing potential to reduce fibrosis effects in a rabbit model.

This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.

This report describes three Saudi sisters with Woodhouse-Sakati syndrome, who exhibited typical features of the condition along with unusual gynecological anomalies.