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Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Non-itchy rashes can indicate serious diseases like lupus.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Human hair follicles can regenerate after removal, but with low success rate.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.