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The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Understanding skin structure and development helps diagnose and treat skin disorders.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.