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Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Finasteride effectively blocks enzyme causing male pattern baldness.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

The study created a new method to test drugs that affect hormone processing in skin.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Tetrathelmis tetrathele extract may help prevent hair loss and improve scalp health.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.