March 2026 in “The Journal of Sexual Medicine” In this study, older women aged 70 and above, treated for sexual dysfunction using carefully monitored hormone therapy, reported improvements in sexual function and symptom relief, with no incidences of cancer or thromboembolic events, though some experienced breast tenderness and hair changes.
1 citations
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December 2012 in “Dermatologic Surgery” Hair transplants can risk reactivating lichen planopilaris, a scarring hair loss condition.
22 citations
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January 2015 in “The Cochrane library” This review found no evidence that DHEA improves quality of life or decreases menopausal symptoms in peri- and postmenopausal women, but it may slightly enhance sexual function compared to placebo.
1 citations
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June 2021 in “Disease and Diagnosis” This case report describes a rare instance of Hashimoto thyroiditis evolving into Graves' disease, emphasizing the potential for such transitions and the importance of early diagnosis and treatment.
9 citations
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April 2015 in “Dermatologic Therapy” This review discusses the use of hormonal therapies for managing acne vulgaris in adult women and reports no new clinical results, emphasizing the chronic and severe nature of acne in this population.
January 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This survey among members of the Association of Hair Restoration Surgeons of India explored the impact of COVID-19 on hair transplant surgery, highlighting challenges posed by halted operations and financial implications.
February 2014 in “아시안뷰티화장품학술지” This review discusses various natural extracts, such as peppermint, rosemary, wild cultivated ginseng, and others, for their potential hair growth promotion effects and calls for further exploration into combinations with fewer side effects.
1 citations
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July 2025 in “Stem Cell Research & Therapy” In this study, researchers evaluated hair follicle transplantation techniques and reported that challenges such as limited follicle supply and low follicle survival rates often limit patient satisfaction, but advances in regenerative medicine may offer promising new solutions.
7 citations
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December 2021 in “Pharmaceutics” This study developed a nanoemulsion of garlic oil and apple cider vinegar loaded with minoxidil to enhance drug permeation through skin, reporting improved ex vivo skin permeation parameters compared to an aqueous dispersion of minoxidil, suggesting potential benefits for treating alopecia areata.
February 2026 in “International Journal of Molecular Sciences” This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.
September 2025 in “Frontiers in Pharmacology” This study suggests that P. orientalis leaf-derived EVs could offer anxiolytic, antidepressant, and sleep-inducing benefits by affecting neurotransmitter levels and reducing inflammation, particularly when administered intranasally.
February 2024 in “Endocrinology and Disorders” This article compiles evidence on prescribing estrogen for hormonal imbalance in women, emphasizing it should be personalized and carefully managed by healthcare providers based on individual cases.
40 citations
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September 2024 in “European Journal of Endocrinology” This study found that global PCOS prevalence in adolescents is 6.3% under new 2023 guideline criteria, compared to 9.8% using Rotterdam criteria; excluding PCOM may prevent over-diagnosis, while recognizing irregular cycles or hyperandrogenism helps avoid under-diagnosis by identifying at-risk individuals for further monitoring.
12 citations
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November 2024 in “International Journal of Molecular Sciences” This study found that hydroxytyrosol significantly alleviated acute liver injury in mice by suppressing inflammation and targeting the TNF-α/PI3K/AKT signaling pathway.
March 2025 in “World Journal of Meta-Analysis” This integrative review analyzed nutritional interventions for Hashimoto’s thyroiditis (HT) and found that treatments such as micronutrient supplementation, anti-inflammatory diets, and lifestyle changes may help manage symptoms, though the effectiveness varied among studies.
January 2026 in “Nutrients” This study observed that while low vitamin D levels are associated with increased risk of autoimmune thyroid diseases, evidence from clinical trials on vitamin D supplementation shows inconsistent effects on thyroid function and disease progression, underscoring the need for further research.
October 2024 in “Journal of the Endocrine Society” This case report describes a rare conversion from Hashimoto's thyroiditis to Graves' disease in a 23-year-old male, requiring a shift from levothyroxine to methimazole and eventually radioactive iodine therapy.
31 citations
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July 2023 in “Nutrients” This article reviews evidence suggesting that vitamin D may help manage Hashimoto’s thyroiditis by affecting immune pathways and improving thyroid function, though more research is needed to fully understand its therapeutic potential.
23 citations
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November 2024 in “Scientific Reports” In this study, researchers found that Hashimoto's thyroiditis patients, despite being in euthyroid status, experienced more severe extrathyroidal symptoms compared to healthy controls, and elevated thyroid antibodies were linked to lower health-related quality of life and increased inflammation.
This study found that in vitro, EGCG may help treat colorectal cancer by targeting iron chelation and the ER stress pathway, leading to apoptosis in cancer cells while sparing normal cells.
49 citations
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July 2004 in “Anesthesiology” This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
December 2024 in “BMC Plant Biology” This study examined Prunus mira populations in the Qinghai-Tibetan Plateau and found high genetic diversity and substantial phylogeographic structure, suggesting geographic isolation limits gene flow; the researchers propose conservation strategies to preserve genetic resources.
3 citations
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July 2023 in “Biomolecules” This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.
13 citations
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July 2019 in “Journal of Biochemical and Molecular Toxicology” In this study on rat dermal papilla cells, hydroxytyrosol, an antioxidant found in olive oil, was reported to protect against oxidative stress, reduce inflammation, and enhance hair growth factors, suggesting its potential to prevent hair loss.
98 citations
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December 2015 in “The Journal of Cell Biology” In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.
66 citations
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May 2012 in “Scientific Reports” This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.
10 citations
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January 2023 in “Journal of the European Academy of Dermatology and Venereology” This review highlights the significant negative impact of alopecia areata on quality of life, mental health, and work, calling for individualized approaches and effective treatments to mitigate these effects.
3 citations
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April 2016 in “PubMed” This study found that a twice-daily regimen of 5% minoxidil foam combined with a botanical hair solution significantly improved hair growth and appearance in men with mild to moderate androgenic alopecia over 12 weeks.
2 citations
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April 2016 in “PubMed” This study found that a 12-week regimen of 2% minoxidil combined with a botanical hair solution improved hair growth and patient satisfaction for female pattern hair loss, aiding treatment adherence.
December 2025 in “Gastroenterology Insights” This study found that IBS is positively associated with psoriasis, rosacea, and urticaria, but inversely associated with acne and vitiligo.