research Periungual Lesions Secondary to Chemotherapy with Docetaxel
Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.
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research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Mitoxantrone
Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
research Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer
Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research The Evolution of Primary Multimodality Treatment in Resectable Breast Cancer
Multimodal primary treatment improves survival in premenopausal breast cancer patients and is also beneficial for postmenopausal women.
research Neuronal Mimicry as a Resistance Phenotype in Cancer Cells
Low dose finasteride causes only small changes in PSA levels in older men with BPH.
research Nutraceuticals Known to Promote Hair Growth Do Not Interfere With the Inhibitory Action of Tamoxifen in MCF7, T47D and BT483 Breast Cancer Cell Lines
Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
research Impact of Low Dose Finasteride for the Treatment of Androgenic Alopecia on Serum Prostate Specific Antigen Levels in Men Participated in Population-Based Screening for Prostate Cancer
Low dose finasteride causes only minor changes in PSA levels in men over 50 with BPH.
research Liarozole: A Novel Treatment Approach for Advanced Prostate Cancer - Results of a Large Randomized Trial Versus Cyproterone Acetate
Liarozole may be more effective than cyproterone acetate for treating advanced prostate cancer, with better PSA response and survival rates, while maintaining quality of life.
research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Forum
The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
research Sericin Hydrogels Promote Skin Wound Healing with Effective Regeneration of Hair Follicles and Sebaceous Glands After Complete Loss of Epidermis and Dermis
Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
research Impact of Substrate Stiffness on Dermal Papilla Aggregates in Microgels
Softer hydrogel surfaces help maintain hair growth-related functions in skin cells.
research Does PSADT After Radical Prostatectomy Predict Overall Survival?—A Report from the SEARCH Database Group
Shorter PSADT after prostate surgery is linked to higher risk of death.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Lignans and Neolignans: Plant Secondary Metabolites as a Reservoir of Biologically Active Substances
Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male
The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
research Two Cases of Low Prostate-Specific Antigen Localized Prostate Cancer Incidentally Detected by Computed Tomography
CT scans can find serious prostate cancer even when PSA levels are low.
research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
research Nutrease Powder - Nature’s Blend of Dietary Protein Nutrients to Maintain Optimum Health in PCOS Disease
Nutrease powder, a high-protein, low-carb supplement, can help manage Polycystic Ovary Syndrome symptoms, regulate periods, improve ovulation, and restore fertility.
research Applications and Risks of Nanomaterials Used in Regenerative Medicine, Delivery Systems, Theranostics, and Therapy
Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
research Monocyclic Aromatic Compounds: Synthesis and Biological Activities
Monocyclic aromatic compounds are important for developing various drugs and treatments.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Recent Progress of Polymeric Microneedle-Assisted Long-Acting Transdermal Drug Delivery
Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.
research Research Advances in Smart Responsive-Hydrogel Dressings for Diabetic Wound Healing
Smart hydrogel dressings could improve diabetic wound healing by adjusting to wound conditions and controlling drug release.