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This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.

In this study, XZYFD, a Traditional Chinese Medicine formulation, was found to improve androgenetic alopecia in a testosterone-induced mouse model by promoting hair regrowth, restoring follicular morphology, and modulating androgen metabolism, MAPK signaling, and lipid metabolism pathways, suggesting potential benefits for patients with metabolic dysfunction.

This study conducted a meta-analysis and found that men with both frontal and vertex male pattern baldness have a slightly increased risk of developing prostate cancer, though most data was from Caucasian populations and effect modification by genetic variations was not assessed.

This review examines the pathophysiology of PCOS and reports that myoinositol may improve menstrual regularity, insulin sensitivity, and reproductive outcomes, with comparable efficacy to metformin and often better tolerability.

This review reported that Withania somnifera (Ashwagandha) significantly improved symptoms like vasomotor disturbances, psychological well-being, and sleep quality in perimenopausal women and was well tolerated, with largely mild side effects in examined trials.

In this case report, researchers describe a 13-year-old phenotypic female with 46,XY karyotype, previously misdiagnosed with androgen insensitivity syndrome, who was later identified to have 17-beta-hydroxysteroid dehydrogenase type 3 deficiency, underscoring the importance of genetic and hormonal tests for accurate diagnosis of sex development disorders.

This review discusses how pesticide exposure leads to hair loss and explores therapeutic options, including conventional and gene therapies, as well as herbal remedies like ginseng and green tea, which may counteract these effects by addressing the toxicological impact on hair follicles.

This review discusses the complex nature, diagnostic approach, and management strategies of polycystic ovary syndrome, emphasizing the importance of individualized care without presenting new clinical findings.

This case report underlines the importance of considering alternative diagnoses like ovarian steroid cell tumors in adolescent females with PCOS-like symptoms when standard treatments fail, highlighting the need for thorough evaluation and early intervention.

In this retrospective cohort study, researchers found that exposure to 5-alpha reductase inhibitors and spironolactone in female alopecia patients was not linked to an increased risk of developing malignant or benign gynecologic tumors when compared to minoxidil use.

This review discusses the pathophysiology, diagnosis, management, and psychosocial impact of skin manifestations in PCOS and emphasizes the need for holistic, personalized care without reporting new results.

In this review, researchers reported that PCOS remains a complex condition with ongoing diagnostic and therapeutic challenges, highlighting recent innovations in diagnosis and treatment that provide alternative options for cases unresponsive to standard care.

In this retrospective study of 133 pediatric patients, topical minoxidil was generally well tolerated for managing androgenetic alopecia, but close monitoring and adherence to treatment, accounting for hormonal and concurrent conditions, were emphasized for effective care.

This review discusses the degenerative effects of anabolic-androgenic steroids on the nervous system and reports no new experimental results, aiming to increase public awareness of their health risks.

This review discusses the genetic differences between male and female pattern hair loss and highlights the uncertainty surrounding genetic factors in female pattern hair loss, but reports no clinical results.

In this study, researchers identified specific SNPs associated with polycystic ovarian syndrome in women from Karnataka, which could improve understanding of genetic mechanisms and aid in future diagnosis and treatment efforts.

This review examines lesser-known factors contributing to polycystic ovarian syndrome and reports no new clinical results, emphasizing the need for further research into individualized treatment and prevention strategies.

This study found that acne prevalence varies among ethnic groups and is often linked to gynecological disorders in women, with hormonal changes as a common factor.

This review discusses the causes and management of hirsutism and suggests improvement can be achieved with a combination of hair removal, suppression of androgen production, and lifestyle changes over 6 to 9 months.

This meta-analysis found that women with polycystic ovary syndrome have over a 2.5-fold higher risk of depression compared to healthy women.

Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

This review discusses the diagnostic criteria and challenges in recognizing polycystic ovary syndrome, noting varied phenotypes and the absence of consensus on renaming the condition; it reports no new findings.

This update discusses guidelines for dermatology nurses and nurse practitioners on polycystic ovary syndrome but presents no new research findings; it emphasizes their role in early diagnosis through recognizing skin symptoms.

This review examines hormonal influences on acne development and available hormonal therapies but reports no new clinical results.

This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.

This review discusses clinical, hormonal, and genetic aspects of nonclassic adrenal hyperplasia and reports no new findings; the condition is highlighted as a potential cause of premature adrenarche and other symptoms in young people.

This study found that women with acne resistant to conventional treatments had significantly higher levels of testosterone, DHEA‑S, prolactin, and LH, suggesting potential underlying hormonal disorders.

This review summarizes existing clinical guidelines for hormonal therapy in gender dysphoria, observing similarities in international practices and emphasizing the need for more evidence-based research, particularly on GnRH agonists for both trans women and men.