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Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Androgens significantly affect female hair loss, and hormonal treatments may help.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Birth control pills increase the risk of blood clots, especially within the first year and with certain types.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

Genetic variations affecting skin structure play a key role in severe acne.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Some alternative treatments for hair loss might work, but more research is needed.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.

Bridging anticoagulation may raise post-surgery bleeding risks.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

STAT5 activation is crucial for starting the hair growth phase.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.