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Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Voriconazole can cause serious side effects, especially in long-term use.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.

Mutant mice help researchers understand hair growth and related genetic factors.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Follistatin helps hair growth and cycling, while activin prevents it.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Aromatase gene variation may increase female hair loss risk.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.