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Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Certain genes control the color of human hair by affecting pigment production.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.