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Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

A new method using NBD-CL can accurately and precisely measure finasteride in medicine, and could be used regularly for quality control in the industry.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

A new method was created to analyze certain chemicals in the urine of alopecia areata patients, revealing they have higher metanephrine content. This method can also be used for other related diseases.

Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.

Chemical hair straightening significantly reduces detectable drug levels in hair.

Hair analysis is better than urine and blood for detecting past drug use.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Men with hair loss may lack zinc, copper, and vitamin D; supplements could help.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Human skin can make serotonin and melatonin.

PGD2 stops hair growth and is higher in bald men with AGA.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

MEL-A from soybean oil can boost fibroblast and papilla cells, potentially aiding hair growth.

Crataegus pinnatifida extract may help increase hair growth and thickness in mice.

Surface and internal treatments can help prevent hair lipid loss during washing.

UV radiation damages hair by creating holes and peeling cuticle layers.

Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.

Raspberry ketone may help grow hair and improve skin elasticity.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.