90 citations,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
69 citations,
April 2010 in “British Journal of Dermatology” Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.
53 citations,
January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
48 citations,
February 2008 in “Nutrition in Clinical Practice” Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.
42 citations,
July 2017 in “Scientific Reports” Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.
37 citations,
June 2018 in “Clinical and Experimental Medicine” People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.
18 citations,
January 2015 in “Journal of obesity and weight loss therapy” Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.
14 citations,
July 2016 in “Fertility and Sterility” Changing the diagnosis criteria for PCOS might miss women at risk for related health issues.
11 citations,
April 2018 in “Nutrition Research” Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.
7 citations,
May 2019 in “Journal of the Formosan Medical Association” HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.
6 citations,
April 2016 in “Journal of the Formosan Medical Association” Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.
2 citations,
July 2022 in “Journal of the Endocrine Society” Some women with PCOS have rare genetic variants linked to the condition.
1 citations,
January 2022 in “Saudi journal of medicine” PCOS is a major cause of infertility in women of childbearing age.
1 citations,
October 2021 in “Prilozi - Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki” Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.
1 citations,
June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
1 citations,
January 2018 in “Annals of Medical and Health Sciences Research” People with male pattern baldness are more likely to have metabolic syndrome.
1 citations,
January 1996 in “Gynecological endocrinology” Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.
149 citations,
December 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
92 citations,
May 2014 in “The American Journal of Medicine” The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.
53 citations,
September 2014 in “Reproductive Biology and Endocrinology” Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.
8 citations,
November 2012 in “Journal of Endocrinological Investigation” Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.
6 citations,
January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
June 2022 in “Biomedical reports” STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.
The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.
70 citations,
March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
54 citations,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
41 citations,
September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
29 citations,
January 2009 in “Gynecological Endocrinology” Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.
8 citations,
June 2020 in “The Journal of Clinical Endocrinology and Metabolism” Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
3 citations,
June 2004 in “Reviews in gynaecological practice” Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.