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This study highlights the role of immune dysregulation, microRNA modulation, and SIRT1 pathways in alopecia areata, suggesting antisense oligonucleotides targeting miR-485-3p as a promising therapeutic strategy for promoting hair regrowth and reducing inflammation in murine models.

This study demonstrates that Wnt signaling plays a crucial mechanoregulatory role in skin regeneration by influencing cellular responses to substrate rigidity, which promotes hair follicle regeneration in the wound-induced hair neogenesis model.

In this experimental study, the researchers observed that Platycladus orientalis leaf extract promoted hair growth by enhancing dermal papilla cell proliferation and increasing growth factor expression, particularly through ACK1 activation and modulation of Wnt/β-catenin signaling pathways in cultured human cells and a 12-week topical application.

In this study, researchers found that topical treatment with adenosine improved hair growth and thickness by significantly increasing hair density and thickness after four months in vivo, with results comparable to minoxidil, potentially due to adenosine's anti-androgenic effects.

This study found that activation of delta-opioid receptors in keratinocytes may delay the expression of the PER2 gene, suggesting a possible link to cancer development through circadian rhythm disruption.

In this study, researchers found that young men with androgenic alopecia exhibited significantly higher mRNA levels of 5α-reductase isozymes and changes in prostate cancer-related genes, which could explain varying responses to treatment and guide future therapies.

This study found that trichoscopy can effectively differentiate scalp psoriasis from seborrheic dermatitis by identifying specific trichoscopic patterns such as hidden hairs, signet ring vessels, and comma vessels.

This study found that individuals with Alopecia Areata experience significantly higher social appearance anxiety compared to healthy controls, driven more by appearance-related concerns than by general anxiety or depression, highlighting the importance of targeted psychosocial assessments in their routine care.

This study observed that women with Polycystic Ovary Syndrome, particularly those with specific phenotypes, had a significantly higher risk of developing kidney stones compared to healthy controls.

This study in Jordan found that topical corticosteroid use is common and often involves creams obtained without prescriptions, with only 61.3% of users aware of potential side effects, highlighting a need for better public education and regulation to prevent misuse.

In this study, the authors used a Bayesian Poisson - Hidden Markov Model to analyze COVID-19 cases by blood type in Europe and Africa, finding differences in hidden states and infection rates based on blood type across these regions.

This report observed that two teenagers developed skin issues, including abscess-like pustules, after taking kelp supplements, which cleared when the supplements were discontinued.

This study found that the proposed Bayesian measurement-error-driven hidden Markov regression model effectively calibrated inflated covariate effect sizes in a community-based survey on androgenetic alopecia regardless of misclassification type.

This review discusses the benefits of non-denatured soybean extracts in skincare, suggesting potential roles in skin lightening, anti-aging, delaying hair growth, and photoprotection, but it reports no new clinical results.

The man has a disease causing skin patches, thickened nerves, and mild muscle weakness.

This study observed that repeated low-depth microneedling in patients with androgenetic alopecia led to initial hair improvement but subsequently caused hair-shaft fragility and breakage, suggesting iatrogenic damage.

This abstract discusses the cosmetic and potential hair growth benefits of almond oil but presents no new empirical research findings.

In this study, continuous use of chemical hair relaxers and curlers was associated with adverse effects such as hair fall, thinning, and scalp irritation in patients with telogen effluvium.

This commentary discusses informal observations of poor or worsening outcomes in some patients after hair transplant surgery for androgenetic alopecia, suggesting the need for further research.

This study found that patients with early onset androgenetic alopecia had significantly higher levels of the biomarker YKL-40, suggesting a link to both the condition's pathogenesis and related metabolic syndrome.

In this paper, the authors propose that a historical decline in dietary tin intake may contribute to cardiovascular issues and accelerate pattern hair loss by causing copper and zinc depletion, which impairs heart function and scalp circulation.

In this paper, the authors propose that a major reduction in dietary tin over the past century could be linked to increased cardiovascular issues and androgenetic alopecia, hypothesizing that tin deficiency disrupts heart function and scalp circulation by depleting copper and zinc.

This study by Moore et al. (2025) provides the first evidence linking C-tactile afferents in humans to hair follicles, showing that these nerve fibers respond to hair movement rather than skin deformation, adding complexity to the understanding of their role in emotion and touch.

The researchers recommend considering porokeratosis as a possible diagnosis for scalp lesions since accurate identification is crucial for management and new treatments like topical cholesterol/lovastatin show promising potential for treating porokeratosis.

This study found that Sri Lankan women with polycystic ovary syndrome experienced higher psychological distress and poorer health-related quality of life, primarily linked to hirsutism rather than obesity.

This review discusses the complexity and genetic organization of human keratin gene clusters and addresses the ongoing need for an updated unified naming system; it reports no new clinical results.

This report suggests that clinically inapparent sweat gland tumors might influence hair loss in a specific patient case.

This study observed no significant relationship between trichoscopic findings and disease severity in male or female androgenetic alopecia, despite some specific patterns correlating with different severity levels in female patients.

This study found that certain trichoscopic patterns, like exclamation mark hairs, were associated with active or mild alopecia areata in Turkish patients, aiding in diagnosis and prediction of the disease.

The digital system for measuring melasma shows promise but needs more development for better accuracy and automation.