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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Nerves are crucial for the regeneration of various body parts in many animals.

The Rotterdam Study aims to understand various diseases in older adults.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Targeted cancer therapies often cause serious skin problems that need careful management.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Myrtle has various health benefits and potential for medicine development.

CDP is crucial for lung and hair follicle cell development.

Stem cell niches support, regulate, and coordinate stem cell functions.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Minoxidil boosts hair growth by increasing cell production and survival.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.