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This study observed that tissue-engineered skin, using VEGF165 gene-modified cells embedded in astragalus polysaccharide-containing 3D printed scaffolds, enhanced early vascularization, and collagen and hair follicle regeneration, leading to improved skin repair in nude mice with full skin defects.

This study found that human hair follicle-derived mesenchymal stem cells demonstrated enhanced wound healing capabilities compared to umbilical cord-derived stem cells in laboratory and animal models.

Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.

In an in-vitro study, researchers found that a specific concentration of Aloe Vera combined with injectable platelet-rich fibrin (i-PRF) significantly increased hair follicle stem cell proliferation compared to Aloe Vera or i-PRF alone, indicating potential benefits for alopecia treatment.

This article discusses the role of hair follicle stem cells in potential breakthroughs for hair cloning and follicular cell implantation, but reports no new clinical findings.

This study found that transplanting hair follicle bulge-derived stem cells in rats enhanced skin regeneration during expansion by differentiating into several skin-related cells and increasing the expression of growth factors.

This study explored the development of GelMet, an electrospun hybrid nanofiber scaffold made from gelatin and PEG methacrylate, which demonstrated strong mechanical properties and effectively supported cell growth in vitro, suggesting its potential for skin tissue engineering applications.

This paper presents a protocol for differentiating human-induced pluripotent stem cells into keratinocyte progenitor cells and keratinocytes, suggesting potential applications for hair follicle restoration and burn or ulcer therapy.

This study found that human induced pluripotent stem cells differentiated precisely to express certain markers during a specific window could enable successful hair follicle generation when transplanted.

This study suggests that adult hair follicle stem cells can survive and potentially differentiate into neuronal cells after being transplanted in a mouse model of traumatic brain injury, indicating promise for TBI therapy.

This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.

This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.

COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.

This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.

This article discusses the coordinated roles of different epidermal stem cells and other cell types in the skin's wound healing process and reports no new experimental results.

This study found that glycolytic metabolism and lactate production are crucial for hair follicle stem cell activation, and manipulating these processes can stimulate the hair cycle.

This study identifies a bipotent stem cell in adult hair follicles that self-renews and contributes to dermal sheath and papilla cell populations, potentially aiding hair regrowth after injury, disease, or aging.

This study found that Wnt signalling activates hair follicle fate in hair follicle stem cells by relieving TCF3/4–TLE-mediated repression, with β-catenin being crucial for this process.

This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.

This study found that stem cells from mouse hair follicles successfully reconstructed the ocular surface in most limbal stem cell deficiency mice, demonstrating potential for treating the condition in a mouse model.

This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.

This study found that Oncostatin M, via JAK-STAT5 signaling, keeps hair follicle stem cells inactive, and its removal leads to hair growth initiation in mice.

This review highlights various methods of stem cell communication that reflect the unique organization and function of different tissues and reports no new results.

This study found that mice lacking the Sept4/ARTS gene had more hair follicle stem cells and improved wound healing, suggesting apoptosis regulation as a potential target in regenerative medicine.

This study found that sympathetic nerves and arrector pili muscles form a niche that modulates hair follicle stem cell activity, revealing their role in hair follicle regeneration.

This study proposes the miR-22-5p-LEF1 axis as a novel pathway that may regulate hair follicle stem cell proliferation.

This study found that mTOR signaling plays a crucial role in activating hair follicle stem cells by balancing BMP-mediated repression, essential for hair regeneration.

This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.