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High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Improving oral hygiene and quitting smoking can resolve black hairy tongue.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

FLCN helps control iron levels in cells.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

Netherton's syndrome is linked to high IgE levels and unique skin and hair symptoms, and may improve with ammonium lactate lotion and allergy management.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.

People with Epidermolysis bullosa have many health problems including poor oral health, which is often neglected due to other medical issues.

Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.

Oral isotretinoin temporarily improved skin symptoms in a child with IFAP syndrome.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Fat cells help recruit healing cells and build skin structure during wound healing.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.

The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.