research Olive And Olive Oil: A One Stop Herbal Solution For The Prophylaxis And Management Of Cardiovascular Disorders
Olive and olive oil help prevent and manage heart diseases.
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research Alleviation of Hyperlipidemia, Insulin Resistance, and Myopathy by Nano Selenium/Nano CoQ10 Platform with Simvastatin in Hyperlipidemic Rats: Comprehensive Outlook
Nano selenium and CoQ10 helped reduce blood fat levels and insulin resistance while preventing muscle damage from statin drugs in rats.
research Toxicity Assessment of the Green Dunaliella Salina Microalgae
Dunaliella salina microalgae is safe to eat and may boost health.
research Efficacy and Safety of Anti-Androgens in the Management of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.
research Plumbagin, A Natural Compound With Several Biological Effects And Anti-Inflammatory Properties
Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Analysis of Finasteride Treatment and Its Withdrawal in Rat Hypothalamus and Hippocampus at Whole-Transcriptome Level
Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Relationship Between Androgen Levels and Blood Pressure in Young Women With Polycystic Ovary Syndrome
High androgen levels in young women with PCOS are linked to higher blood pressure.
research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Adverse Reactions to Oral Retinoids: An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Metformin Therapy for the Reproductive and Metabolic Consequences of Polycystic Ovary Syndrome
Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.
research Hair-Root Adaptation to Marasmus in Andean Indian Children
Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment
Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
research Use of Metformin in Pediatric Age
Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Generalized Calcinosis Cutis Associated with Probable Leptospirosis in a Dog
A dog's skin calcification condition resolved without treatment after a bacterial infection.
research Safety and Efficacy of Transdermal Testosterone for Treatment of Hypoactive Sexual Desire Disorder
Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
research The Role of Metformin in the Management of Polycystic Ovary Syndrome
Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
research Nanoemulgel as an Innovative Platform for Phytomolecules
Nanoemulgel improves delivery and effectiveness of plant-based drugs for various conditions.
research Crystallization and Preliminary X-Ray Analysis of the Human Androgen Receptor Ligand-Binding Domain with a Coactivator-Like Peptide and Selective Androgen Receptor Modulators
Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.
research Metformin Effects on Polycystic Ovarian Syndrome
Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.
research Spironolactone
Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.
research Polycystic Ovary Syndrome: Comprehensive Overview
PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
research Timing of Expression of the Core Clock Gene Bmal1 Influences Its Effects on Aging and Survival
The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
research A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control
Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension
Minoxidil effectively treats severe hypertension, but watch for side effects.