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The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Niosomes are a promising and effective way to deliver drugs through the skin.

Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.

Terazosin and finasteride together cause no major issues.

The conclusion is that more research is needed to better understand and treat adult acne, and that patient education and simple treatment plans are important for better results.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

The normal human prostate does not significantly affect blood DHT levels.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.

Fat cells are important for tissue repair and stem cell support in various body parts.

There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Transplant patients often get skin problems, with treatments varying by condition.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Finasteride gel effectively and safely reduces hair thickness in women with excessive hair growth.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Eating less can improve stem cell function and increase lifespan.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.