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Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.

The dog died from myxedema coma linked to severe atherosclerosis and thyroid issues.

Lower LDL-c levels predict higher COVID-19 mortality.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

New treatments for children's scalp ringworm are recommended based on recent data.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Mycophenolate mofetil can effectively treat autoimmune hepatitis when standard drugs fail.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

People with chronic Hepatitis C often have skin problems like itching and contact dermatitis, especially older individuals and women.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.