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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Finasteride safely lowers DHT levels without affecting testosterone.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Hair loss linked to higher heart disease risk in both men and women.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.