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    Glossary HAIR-AN Syndrome

    condition with high male hormones, insulin resistance, dark skin patches

    HAIR-AN Syndrome, which stands for Hyperandrogenism-Insulin Resistance-Acanthosis Nigricans Syndrome, is a condition characterized by excessive levels of male hormones (hyperandrogenism), resistance to insulin, and dark, velvety skin patches (acanthosis nigricans). This syndrome is often associated with polycystic ovary syndrome (PCOS) and can lead to symptoms like irregular menstrual cycles, severe acne, and excessive hair growth.

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    Research 30 of 603

    1. Acanthosis Nigricans during an HAIR-AN syndrome: "The Tree That Hides the Forest" Journal of clinical & experimental dermatology research · 2017
    2. Clinical Profiles, Occurrence, and Management of Adolescent Patients with HAIR-AN Syndrome 2004 · 24 citations
    3. Successful Treatment of Hirsutism in HAIR-AN Syndrome Using Flutamide, Spironolactone, and Birth Control Therapy Archives of dermatology · 1997 · 17 citations
    4. An adolescent girl with coexisting ovarian mature cystic teratoma and HAIR-AN syndrome, an extreme subtype of polycystic ovarian syndrome Endocrinology, diabetes & metabolism case reports · 2021 · 2 citations
    5. HAIR-AN Syndrome: A Systematic Review of Clinical, Metabolic, and Hormonal Features in Women of Reproductive Age Research Square (Research Square) · 2026
    6. A Complex Clinical Situation in Polycystic Ovary Syndrome: HAIR‐AN Syndrome ‘‘Case Report’’ Case Reports in Medicine · 2025
    7. Combination of metformin with liraglutide in treating HAIR-AN syndrome in children: A case report and literature review. PubMed · 2023
    8. A Rare Case of Adolescent Girl with Beard-PCOS with a Difference: “HAIR-AN Syndrome” 2022
    9. The Hair-An Syndrome: A Report of a Misdiagnosed Case with Unfortunate Outcome 1998
    10. The HAIR-AN syndrome : a case report 1995
    11. Increased Insulin Sensitivity by Metformin Enhances Intense-Pulsed-Light-Assisted Hair Removal in Patients with Polycystic Ovary Syndrome Dermatology · 2008 · 17 citations
    12. Acanthosis nigricans and the metabolic syndrome Clinics in Dermatology · 2017 · 30 citations
    13. Acne-Associated Syndromes Springer eBooks · 2019
    14. Syndromes of Severe Insulin Resistance (SSIRs) 2004
    15. HAIR AND SYSTEMATIC DISEASE Dermatologic Clinics · 2001 · 58 citations
    16. Non polycystic ovary syndrome–related endocrine disorders associated with hirsutism European Journal of Clinical Investigation · 2011 · 39 citations
    17. Mania in Hyperandrogenism, Insulin Resistance, and Nigricans Acanthosis Syndrome ˜The œAmerican journal of psychiatry · 2002 · 3 citations
    18. Hyperandrogenism insulin resistance-acanthosis nigricans syndrome in a female adolescent with migraine: A case report Indian Journal of Physiology and Pharmacology · 2025
    19. Hyperandrogenism-insulin resistance-acanthosis nigricans syndrome with PCOS and Hashimoto's thyroiditis: case report International Journal of Research in Medical Sciences · 2015
    20. Overnight loss of pigmented hair in autoimmune autonomic neuropathy treated with IVIg Neurology Neuroimmunology & Neuroinflammation · 2019 · 2 citations
    21. Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients Journal of the European Academy of Dermatology and Venereology · 2014 · 16 citations
    22. A rational approach to the diagnosis of polycystic ovarian syndrome during adolescence Arquivos Brasileiros De Endocrinologia E Metabologia · 2011 · 26 citations
    23. Female Adolescent Hair Disorders Journal of Pediatric and Adolescent Gynecology · 2009 · 20 citations
    24. Hyperandrogenism-Insulin Resistance-Acanthosis Nigricans Syndrome Case reports in endocrinology · 2015 · 7 citations
    25. Cardiovascular risk factors and events in women with androgen excess Journal of Endocrinological Investigation · 2014 · 31 citations
    26. Acne as a chronic systemic disease Clinics in Dermatology · 2013 · 71 citations
    27. The clinical evaluation of hirsutism Dermatologic therapy · 2008 · 67 citations
    28. Hirsutism: Diagnosis and management Gender Medicine · 2010 · 41 citations
    29. Mixed Form of Hirsutism in Adolescent Females and Laser Therapy Iranian Red Crescent medical journal · 2014 · 7 citations
    30. Acne in Dark Skin Springer eBooks · 2018 · 5 citations