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    Glossary Hair Patterning

    natural arrangement and distribution of hair on the body

    Hair patterning refers to the natural arrangement and distribution of hair on the scalp and body, influenced by genetic, hormonal, and environmental factors. It includes the direction, density, and growth cycles of hair, which can vary significantly among individuals and can be affected by conditions like alopecia or androgenetic hair loss.

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    1. Hierarchical patterning modes orchestrate hair follicle morphogenesis PLoS Biology · 2017 · 149 citations
    2. Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse Journal of Investigative Dermatology · 2009 · 92 citations
    3. Epidermal patterning and induction of different hair types during mouse embryonic development Birth defects research · 2009 · 81 citations
    4. Mesenchymal cell specific deletion of Tsc2 regulates hair follicle development and patterning Journal of dermatological science · 2016
    5. 726 The Wnt-inhibitor Dkk4 is required for primary hair follicle induction and patterning Journal of Investigative Dermatology · 2022
    6. 318 The Wnt-inhibitor Dkk4 is required for primary hair follicle induction and patterning Journal of Investigative Dermatology · 2021
    7. Observations of root hair patterning in soils: Insights from synchrotron-based X-ray computed microtomography Plant and Soil · 2024
    8. 1469 Tissue mechanics partake in spatiotemporal patterning of wound-induced hair neogenesis in African spiny mouse Journal of Investigative Dermatology · 2018
    9. Order from disorder: Self-organization in mammalian hair patterning Proceedings of the National Academy of Sciences · 2006 · 91 citations
    10. Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C Advanced Science · 2025
    11. Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration Nature Communications · 2022
    12. Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology Journal of Visualized Experiments · 2014 · 27 citations
    13. Author response: A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning 2017 · 3 citations
    14. Decision letter: A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning 2017
    15. Self‐organizing hair peg‐like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field Experimental Dermatology · 2019 · 26 citations
    16. The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice PLoS Biology · 2026
    17. 0928 Dkk4 fine-tunes Wnt activity for hair follicle patterning and initiation Journal of Investigative Dermatology · 2026
    18. Faculty Opinions recommendation of Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2022
    19. Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation Development · 2012 · 207 citations
    20. When whorls collide: the development of hair patterns in frizzled 6 mutant mice Development · 2010 · 55 citations
    21. EEMCO Guidance for the Assessment of Hair Shedding and Alopecia Skin Pharmacology and Physiology · 2004 · 51 citations
    22. Module-based complexity formation: periodic patterning in feathers and hairs Wiley Interdisciplinary Reviews-Developmental Biology · 2012 · 47 citations
    23. Hair science and technology Micron · 2003 · 3 citations
    24. 1392 Dkk4 regulates Wnt-dependent hair formation and pattern Journal of Investigative Dermatology · 2023
    25. 872 Dermal Wnt/β-catenin signaling controls hair follicle dermal condensate size during development Journal of Investigative Dermatology · 2017
    26. 0882 Patterning and regional specification of hairy skin Journal of Investigative Dermatology · 2025
    27. Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials Experimental Dermatology · 2018 · 41 citations
    28. A prostaglandind-synthase-positive mast cell gradient characterizes scalp patterning Journal of Cutaneous Pathology · 2013 · 6 citations
    29. ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change Journal of experimental botany · 2013 · 161 citations
    30. Deciphering principles of morphogenesis from temporal and spatial patterns on the integument Developmental Dynamics · 2015 · 19 citations