39 citations,
May 2014 in “Frontiers in Pharmacology” Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
36 citations,
January 2018 in “Burns & Trauma” NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.
26 citations,
August 1971 in “Journal of Morphology” Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.
24 citations,
May 2019 in “PLOS ONE” The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
24 citations,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
24 citations,
July 2017 in “Structure” FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
23 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
17 citations,
June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
14 citations,
February 2020 in “Stem Cells International” Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
13 citations,
August 2020 in “Frontiers in Immunology” Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
11 citations,
July 2021 in “Nanomaterials” Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.
10 citations,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
3 citations,
May 2021 in “Archiv der Pharmazie” SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
January 2024 in “Burns and trauma” The skin microbiome helps heal wounds and can be targeted to improve healing.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
April 2018 in “Journal of Investigative Dermatology” The study found that p63 needs signals from morphogens to help skin cells differentiate properly.
May 2015 in “Journal of The American Academy of Dermatology” Treatment with biologic agents can significantly improve psoriasis symptoms, and blood biomarkers could potentially predict individual patient's response to treatment.
February 2014 in “Plastic and Reconstructive Surgery” I'm sorry, but I can't provide a summary as no specific information or context was given in your request.
3 citations,
September 2017 in “Stem cell investigation” PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.
November 2023 in “Zenodo (CERN European Organization for Nuclear Research)” The dataset includes detailed genetic information from mouse skin cells before and after injury.
November 2023 in “Zenodo (CERN European Organization for Nuclear Research)” The dataset includes detailed genetic information from mouse skin cells before and after injury.
1 citations,
January 2022 in “Springer eBooks” 17 citations,
November 2015 in “Oxidative Medicine and Cellular Longevity” Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.
1 citations,
March 2023 in “Science Translational Medicine” Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
February 2022 in “Journal of Investigative Dermatology” Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.
Skin tumor cells in patients with tuberous sclerosis have higher levels of a protein called cathepsin B.
September 2023 in “Journal of Fluid Mechanics” The homogenization theory effectively describes how flow behaves differently across asymmetric membranes.