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The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Wound healing insights can improve regenerative medicine.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Loss of keratin K2 causes skin problems and inflammation.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Artificial skin is improving wound healing and shows potential for treating different types of wounds.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.