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    Glossary Hair Follicle Apoptosis

    programmed cell death within hair follicles

    Hair follicle apoptosis refers to the programmed cell death of cells within the hair follicle. This process is a natural part of the hair growth cycle, particularly during the transition from the growth phase (anagen) to the regression phase (catagen), and it helps regulate hair growth and shedding.

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    1. Hair Follicle Apoptosis and Bcl-2 Journal of Investigative Dermatology Symposium Proceedings · 1999 · 54 citations
    2. The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function EMBO Reports · 2021 · 10 citations
    3. Pathobiology of the hairless phenotype: Dysregulation of hair follicle apoptosis and topobiology during the initiation of follicle cycling Journal of Dermatological Science · 1998 · 9 citations
    4. Yangxuebushen Decoction prevents cyclophosphamide-induced hair loss by inhibiting hair follicle apoptosis Cutaneous and Ocular Toxicology · 2026
    5. Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis Dermatologic Surgery · 2004 · 10 citations
    6. Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis Dermatologic Surgery · 2004
    7. Apoptotic Cells May Drive Cell Death in Hair Follicles During their Regression Cycle bioRxiv (Cold Spring Harbor Laboratory) · 2020
    8. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo andIn Vitro Journal of Investigative Dermatology · 1998 · 140 citations
    9. Apoptosis in growing hair follicles following gamma-irradiation and application for the evaluation of radioprotective agents. PubMed · 2004 · 10 citations
    10. Apoptotic cells may drive cell death in hair follicles during their regression cycle Oncotarget · 2023
    11. Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue Journal of Molecular Histology · 2015 · 6 citations
    12. Human placenta induces hair regrowth in chemotherapy-induced alopecia via inhibition of apoptotic factors and proliferation of hair follicles BMC Complementary Medicine and Therapies · 2020 · 4 citations
    13. Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage ˜The œFASEB journal · 2006 · 210 citations
    14. A role for p75 neurotrophin receptor in the control of apoptosis‐driven hair follicle regression The FASEB Journal · 2000 · 96 citations
    15. Panax ginseng prevents apoptosis in hair follicles and accelerates recovery of hair medullary cells in irradiated mice. PubMed · 1998 · 22 citations
    16. Apoptotic cell death in canine hair follicle. PubMed · 2005 · 5 citations
    17. Cyclosporin inhibits the apoptosis and effects the mRNA expressions of selected growth factors in cultured mouse hair follicles Journal of Clinical Dermatology · 2003
    18. Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization Oxidative Medicine and Cellular Longevity · 2022 · 20 citations
    19. Complex Changes in the Apoptotic and Cell Differentiation Programs during Initiation of the Hair Follicle Response to Chemotherapy Journal of Investigative Dermatology · 2014 · 12 citations
    20. DNA methylation of microRNA-365-1 induces apoptosis of hair follicle stem cells by targeting DAP3 Non-coding RNA Research · 2024 · 7 citations
    21. Effect of Topical Grape Sap on Apoptosis in Hair Follicle Among Male Rats Gene, cell and tissue · 2021 · 1 citations
    22. A single-cell transcriptomic atlas elucidates the hair cycle and apoptosis mechanisms in goat hair follicles Frontiers in Cell and Developmental Biology · 2025
    23. Anti-CXCL4 monoclonal antibody accelerates telogen to anagen transition and attenuates apoptosis of the hair follicle in mice Experimental and Therapeutic Medicine · 2017
    24. [Apoptotic study on the effect of fluorine and selenium on the human hair follicle in vitro]. PubMed · 2007
    25. Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview Biomolecules · 2023 · 1 citations
    26. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations
    27. Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle Journal of Dermatological Science · 2004 · 149 citations
    28. Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)? 1998 · 130 citations
    29. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression American Journal of Pathology · 2006 · 128 citations
    30. Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege Journal of Investigative Dermatology · 2013 · 53 citations