January 2024 in “JAAD case reports” Netherton syndrome can cause severe and chronic vulvovaginal symptoms that may improve with continuous oral contraceptives.
July 2023 in “The Egyptian Journal of Hospital Medicine ” The conclusion is that emotional support and a variety of treatments are important for alopecia areata, but more research is needed.
April 2023 in “Journal of Investigative Dermatology” This study investigated the role of CD8+ effector memory cells re-expressing CD45RA (TEMRA) in rapidly progressive alopecia areata (RPAA) and their potential to predict therapeutic outcomes following intravenous corticosteroid pulse therapy (IVPT). Involving 26 RPAA patients, the study found that TEMRA cells were significantly increased in non-responders (those with < 50% hair regrowth) compared to responders, both before and after IVPT. Non-responders' TEMRA cells exhibited 3.3-fold greater cytotoxicity when exposed to trichohyalin. Histological analysis showed a higher proportion of TEMRA cells in non-responders' peribulbar regions, correlating with their frequency in peripheral blood mononuclear cells (r = 0.74). These results suggest that monitoring TEMRA cells could help evaluate disease activity and predict therapeutic outcomes in RPAA.
December 2022 in “International Journal of Women's Dermatology” The Sinclair Shedding Scale is effective for diagnosing Alopecia Areata Incognita and monitoring treatment success.
March 2022 in “Wound practice & research” New treatments for alopecia areata show promise, but standardized guidelines are needed.
January 2022 in “Journal of Skin and Stem Cell” Trichodynia is a painful scalp condition needing targeted treatments beyond symptom management.
January 2022 in “Yonago Acta Medica” A woman got a skin condition from misusing a steroid cream, which improved after she stopped using it and started a new treatment.
Fractional CO2 laser is more effective and safer than steroid injections for treating alopecia areata.
Tinea capitis in adults often leads to misdiagnosis or delayed diagnosis due to atypical symptoms, requiring careful examination for proper treatment.
A 29-year-old woman with symptoms of both lupus and rheumatoid arthritis improved with specific medications.
178 citations,
February 2018 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
89 citations,
October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
61 citations,
October 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The document concludes that accurate diagnosis is crucial for effectively treating common scalp disorders, which often have similar symptoms.
60 citations,
June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
48 citations,
November 2018 in “Journal of dermatological treatment” Women are more likely to have Lichen planopilaris, and treatments with cyclosporine and methotrexate are most effective but less safe than mycophenolate mofetil.
48 citations,
April 2021 in “Journal of the American Academy of Dermatology” Topical corticosteroids are the best initial treatment for children's alopecia areata.
42 citations,
December 2004 in “Paediatric Respiratory Reviews” Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.
40 citations,
May 2020 in “Cureus” The conclusion is that treatments for Telogen Effluvium exist, but standard treatment guidelines are needed.
39 citations,
March 2017 in “Dermatologic clinics” UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
36 citations,
November 2000 in “Journal of the American Academy of Dermatology” A woman with dermatomyositis showed rare skin symptoms, was treated successfully, and her case suggests checking for cancer in similar patients.
34 citations,
December 2011 in “The Journal of Dermatology” A unique type of lupus panniculitis causes reversible hair loss on the scalp in East Asians.
33 citations,
May 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
33 citations,
November 2006 in “Survey of Ophthalmology” Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.
24 citations,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
20 citations,
October 2003 in “The Journal of Dermatology” DCP therapy causes side effects like weakness, flushing, headaches, and taste changes, but less frequently causes hypertension and diabetes.
17 citations,
May 1998 in “Contact Dermatitis” Minoxidil can cause pustular allergic reactions on skin.
14 citations,
January 1985 in “International Journal of Dermatology” The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.
7 citations,
August 2021 in “Journal of the European Academy of Dermatology and Venereology” Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
7 citations,
October 2019 in “Annals of palliative medicine” New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.
6 citations,
November 2018 in “Case reports in nephrology and dialysis” Rituximab may be an effective treatment for Cronkhite-Canada syndrome with kidney disease.