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The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

HFMs can help study hair growth and test potential hair growth drugs.

Sabal and Urtica extract works as well as finasteride for treating BPH, with fewer side effects.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Wnt signaling is crucial for skin wound healing and reducing scars.

Lamins are vital for cell survival, organ development, and preventing premature aging.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

RTA 408 cream protects mice from radiation skin damage.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Citrullus colocynthis has pain-relieving, anti-inflammatory, antidiabetic, and hair growth benefits, but can cause side effects like colic and diarrhea.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.