1 citations,
February 2004 Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.
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April 2024 in “Applied biological chemistry” Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.
134 citations,
July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
1 citations,
November 2011 in “British journal of pharmacology” Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
34 citations,
July 2003 in “Archives of Facial Plastic Surgery” Proper incision techniques can make face-lift scars less noticeable.
7 citations,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
8 citations,
November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
80 citations,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
66 citations,
July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
January 2012 in “Journal of Investigative Dermatology” Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
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15 citations,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
49 citations,
March 2017 in “PubMed” Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
143 citations,
May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
December 2022 in “Türk biyokimya dergisi” The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.
3 citations,
May 2018 in “European Journal of Dermatology” Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.
Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.
December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
33 citations,
March 2018 in “Trends in cell biology” Metabolism plays a key role in determining stem cell fate.
30 citations,
October 2010 in “Journal of The American Academy of Dermatology” The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.
4 citations,
August 2011 in “Aktuelle Dermatologie” Topical melatonin is a safe treatment that may reduce hair loss in people with androgenetic alopecia.
51 citations,
November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
75 citations,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
68 citations,
November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
14 citations,
August 2009 in “Cancer epidemiology” AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.
October 2022 in “Frontiers in Endocrinology” New tools show that in fish, NPY increases feeding and somatostatin decreases it.
January 2023 in “Karger Kompass. Dermatologie” Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
5 citations,
October 2021 in “Clinical, cosmetic and investigational dermatology” Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.
4 citations,
August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science” Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.