19 citations
,
March 2021 in “Experimental dermatology” This review discusses recent progress in understanding the cellular mechanisms of sebaceous gland development and maintenance, emphasizing the role of stem and progenitor cells in related skin pathologies, and reports no new results.
8 citations
,
April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
1 citations
,
March 2009 in “China Journal of Chinese Matera Medica” This review discusses the pharmacological effects and potential mechanisms of procyanidins, noting its roles in antioxidation, cardiovascular protection, and more, but reports no new clinical results.
February 2026 in “Nature Communications” This study combined spatial and single-cell transcriptomics to identify that hypercontractility of the connective tissue sheath activates PIEZO1 in hair follicles, leading to miniaturization in male androgenetic alopecia, and found that inhibiting this contraction improves hair growth in models.
January 2024 in “Deleted Journal” This review reports that while essential oils are popular for hair health benefits like growth stimulation and hair quality improvement, scientific evidence supporting these claims remains limited and inconclusive.
June 2023 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” This review discusses platelet-rich plasma as a treatment for androgenetic alopecia and explains its mechanisms, but presents no new clinical results.
5 citations
,
October 2013 in “Experimental Dermatology” This study observed that putrescine and HR form a negative feedback mechanism affecting hair cycling, indicating a significant connection between HR, polyamines, and hair growth regulation.
May 2025 in “Current Drug Safety” In this case study, a 17-year-old male using topical minoxidil 5% for beard growth developed peripheral edema, which resolved after discontinuing the drug, highlighting a rare but significant systemic side effect of minoxidil's use.
July 2024 in “Journal of Investigative Dermatology” This study suggests that macrophages, especially CD206+ subsets, play a key role in hair growth induced by squaric acid dibutyl ester, a therapy used for alopecia areata.
August 2023 in “Journal of Investigative Dermatology” Senescent melanocytes in nevus skin boost hair growth.
August 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review discusses the pharmacology, mechanism of action, clinical efficacy, and adverse events of topical minoxidil for hair loss but reports no new clinical findings.
97 citations
,
May 2019 in “Frontiers in Cell and Developmental Biology” This review examines the interaction between the extracellular matrix and immune cells in skin diseases and evaluates advanced therapies that target involved molecular mechanisms, reporting no new clinical findings.
83 citations
,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
15 citations
,
September 2018 in “Frontiers in Plant Science” This study identified that downregulation of the gene BcFLA1 decreases root hair length in Brassica carinata under phosphate-deficient conditions, highlighting its role in root hair elongation.
5 citations
,
January 2019 in “Elsevier eBooks” This chapter reviews skin components, wound healing mechanisms, and the potential of biomaterials to enhance skin repair and regeneration, without offering new experimental results.
3 citations
,
June 1981 in “PubMed” This article reviews the skin changes that can occur with hormonal contraceptive use and highlights various mechanisms and potential treatment strategies but reports no new clinical results.
1 citations
,
January 2026 in “Science Advances” This study developed a 3D bioprinted skin model to mimic pemphigus vulgaris, providing a tool to study disease mechanisms and test targeted therapies by reproducing the architecture and pathogenic disruptions of native skin.
May 2026 in “International Journal of Drug Delivery Technology” This review discusses PRP therapy's history, mechanisms, and innovations in its use across various medical fields, but provides no new clinical results; the authors highlight challenges like standardization and regulatory issues.
February 2024 in “International Journal of Molecular Sciences” This review outlines the functional anatomy, pathology, and molecular mechanisms of androgenetic alopecia, emphasizing the need for multi-omics approaches to better understand this condition's biology.
111 citations
,
April 2006 in “Annals of the New York Academy of Sciences” This study found that preventing abnormal mineral ion homeostasis in vitamin D receptor knockout mice stopped bone abnormalities, while the animal's skin phenotype arose from direct receptor effects independent of vitamin D.
5 citations
,
July 2019 in “Atlas of the Oral and Maxillofacial Surgery Clinics” This article discusses challenges and limitations of using simple tissue mechanics for repairing head and neck skin defects in trauma and does not report new findings; it highlights potential problems with routine methods.
November 2023 in “Frontiers in veterinary science” In this study, researchers used yaks as a natural model to investigate hair growth mechanisms, overcoming previous limitations by establishing in vitro models of hair follicle-associated cells and optimizing methods for cell culture and differentiation.
1 citations
,
July 2013 in “Hair transplant forum international” This abstract lacks results; it aims to understand hair follicle regulation mechanisms but does not report specific findings or data.
January 2025 in “Antioxidants” In this study, repetitive subcutaneous administrations of a conditioned medium from stem cells significantly suppressed hair graying in mice exposed to X-ray irradiation, likely through antioxidative mechanisms involving HGF and potentially VEGF.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.
September 2025 in “Ankara Universitesi Eczacilik Fakultesi Dergisi” This study analyzed the therapeutic potential of various plant species for alopecia areata treatment, highlighting their possible benefits due to anti-inflammatory and immunomodulatory properties, though more research is needed to fully understand the mechanisms involved.
75 citations
,
June 2019 in “International Journal of Molecular Sciences” This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.
65 citations
,
December 2000 in “PubMed” This article reviews key questions in skin biology, particularly the mechanisms of hair follicle patterning and the role of stem cells in the epidermis, reporting no new results.
52 citations
,
October 2012 in “Journal of Dermatological Science” This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.
47 citations
,
June 1996 in “International Journal of Legal Medicine” This article discusses how drug molecules integrate into hair fibers, focusing on biological transport mechanisms and physicochemical factors, but reports no new experimental findings.