The Role of Platelet-Rich Plasma in Androgenetic Alopecia: A Comprehensive Narrative Review

June 2023 in “ GLOBAL JOURNAL FOR RESEARCH ANALYSIS ”

Mariá Camila Ospina Ríos

TLDR PRP is a promising treatment for hair loss.

Platelet-rich plasma (PRP) is a promising treatment for androgenetic alopecia (AGA) due to its high concentration of growth factors and bioactive molecules that aid in tissue repair and wound healing. PRP stimulates hair growth and regeneration by releasing growth factors such as PDGF, TGF-β, VEGF, and IGF, which promote cell proliferation, activate dormant hair follicles, and induce hair cycle growth. Additionally, PRP reduces inflammation, promotes angiogenesis, and may inhibit 5-alpha reductase activity, contributing to its effectiveness in treating AGA. Understanding these mechanisms allows for the optimization of PRP in hair restoration therapies.

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Related Research

1 / 1 results

research Heterogeneity in Amount of Growth Factors Secreted by Platelets in Platelet-Rich Plasma Samples from Alopecia Patients

8 citations, August 2020 in “Experimental dermatology”

PRP therapy for alopecia shows inconsistent results due to natural variability in growth factor secretion by platelets.