research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
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research Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency: Pathophysiology, Diagnosis, and Treatment
The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research Congenital Adrenal Hyperplasia: Comprehensive Overview and Clinical Management
The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.
research 5α-Reductase Isozymes and Androgen Actions in the Prostate
5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
research Exploring the Impact of Ovariectomy on Hair Growth: Can Ovariectomized Mouse Serve as a Model for Investigating Female Pattern Hair Loss in Humans?
research Is Increased Constitutive Skin and Hair Pigmentation an Early Sign of Puberty?
Darker skin in 10-year-old girls may be an early sign of puberty.
research Feminizing Adrenocortical Carcinoma Without Gynecomastia
A man with a rare adrenal cancer showed unusual symptoms and died four months after diagnosis.
research Chemistry, Pharmacology, and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Alcohol and Prostate Cancer: Time to Draw Conclusions
Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
research Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Tamoxifen for Flutamide/Finasteride-Induced Gynecomastia
Tamoxifen effectively treats gynecomastia without causing impotence.
research Acupuncture in Polycystic Ovary Syndrome: Potential and Challenges
Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.
research Ovarian Hypertension: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Differential Diagnosis of Hyperandrogenism in Women with Polycystic Ovary Syndrome
The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.
research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?
Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Finasteride for Prostatic Disease: An Updated and Comprehensive Review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Adverse Effects of Common Medications on Male Fertility
Some common medications can harm male fertility, but many effects can be reversed.
research Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research Androgen Deprivation Therapy in Prostate Cancer: Focusing on Sexual Side Effects
Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
research 25 Years of Estrogen Receptor Beta: A Personal Journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction
High levels of androgens during early development may cause PCOS-like symptoms.
research Recent Advances in Oxasteroids Chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.