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Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Neurohormones help control skin health and could treat skin disorders.

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

The testes produce sperm and hormones essential for male development.

SHBG may be a useful early indicator and treatment target for PCOS.

Girls with PCOS and menstrual disorders have notably higher androgen hormone levels.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Moving horses to new places can increase their stress levels, as shown by higher stress hormone in their hair.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Thyroid-related genes are active in skin cells and may affect autoimmune conditions.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Melatonin may help manage PCOS by improving insulin sensitivity, hormone balance, and mood.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Stress can stop hair growth in mice, and treatments can reverse this effect.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Low zinc and selenium levels in sheep are linked to hair loss and thyroid problems.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

The new rodent model successfully mimics non-lean human PCOS symptoms.

The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.

The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.