research IGFBP-rP1 Is a Potential Therapeutic Target in Androgenic Alopecia
IGFBP-rP1 could be a new treatment for a common type of hair loss.
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research Role of Collagen VI in Peripheral Nerves and Wound-Induced Hair Regrowth
Collagen VI is crucial for nerve function and affects wound-induced hair regrowth.
research Severe Impact of Late Diagnosis of Congenital Adrenal Hyperplasia on Gender Identity, Sexual Orientation, and Function: Case Report and Review of the Literature
Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.
research Growing Up Fast: Managing Autism Spectrum Disorder and Precocious Puberty
The document discusses a young boy with autism and early puberty but does not provide a conclusion on managing his behavior.
research Congenital Generalized Hypertrichosis: The Skin as a Clue to Complex Malformation Syndromes
The document reviewed congenital generalized hypertrichosis, a rare condition characterized by excessive body hair growth, which could be isolated or part of complex malformation syndromes. It distinguished hypertrichosis from hirsutism and classified it based on onset, distribution, and association with other anomalies. While congenital hypertrichosis was rare, acquired hypertrichosis was more common and linked to various causes like drug side effects and metabolic disorders. The review highlighted that hypertrichosis often accompanied other clinical signs such as intellectual delay and epilepsy. A 20-year follow-up of a previously described patient was also discussed, emphasizing the condition's role as an indicator of complex syndromes.
research Effects of Anti-EGF Serum on Newborn Mice
The study from 1988 investigated the effects of anti-EGF serum on newborn mice, finding that it delayed eyelid opening and incisor tooth eruption, accelerated hair growth, and delayed weight gain. These findings suggested that epidermal growth factor (EGF) played a physiological role in the first week after birth, which could be disrupted by the administration of anti-EGF serum.
research Hair Product Allergy: A Review of Epidemiology and Management
Hair product allergies are common, especially to hair dyes, and hairdressers are at higher risk.
research Dermatologic Applications of Direct-to-Consumer Genomic Analysis
Living near more dermatologists and using certain cancer screening tests lowers the chance of being diagnosed with advanced skin cancer.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Toward a Diagnostic Score in Cushing's Syndrome
The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
research Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus
Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
research Tumor Suppressor Activity of ODC Antizyme in MEK-Driven Skin Tumorigenesis
The study tested whether suppressing ornithine decarboxylase (ODC) activity could block skin tumor promotion in mice with activated MEK mutations. By crossing these mice with those overexpressing antizyme (AZ), which degrades ODC, researchers found that AZ expression significantly delayed tumor development and reduced tumor numbers. This effect was most pronounced in MEK/K6-AZ mice, which had fewer than one tumor per mouse after 8 weeks, compared to over 13 tumors in MEK-only mice. The study suggested that AZ primarily inhibited putrescine accumulation, slowing cell growth by increasing G2/M transit time, without inducing apoptosis.
research Nonscarring Hair Loss Disorders
Most types of hair loss can regrow naturally, but there are no effective cures for male pattern or age-related hair loss, and only limited options for females.
research Activin B Promotes Epithelial Wound Healing In Vivo Through RhoA-JNK Signaling Pathway
Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.
research Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation
MMP-9 is essential for proper hair canal formation.
research Capitalizing on Aging Anxieties: Promissory Discourse and the Creation of an Anti-Aging Treatment Market
The anti-ageing treatment market is growing by exploiting fears of ageing with unproven promises, which could harm public trust and genuine science.
research Newborn Screening for Biotinidase Deficiency: Pilot Study and Follow-Up of Identified Cases
Newborn screening for biotinidase deficiency is effective in preventing severe complications.
research Effects of Some Chemicals in Cosmetic Products on Pregnant, Fetus, and Newborn Health
Some chemicals in cosmetics may harm pregnant individuals, fetuses, and newborns, and should be avoided unless necessary.
research Ten Pearls Every Dermatologist Should Know About the Appropriate Use of Relaxers
Dermatologists should use hair relaxers carefully to avoid hair and scalp damage, following specific guidelines for application and maintenance.
research Male Androgenetic Alopecia
Hair loss in men can be slowed or reversed with treatments like minoxidil and finasteride, but it resumes if treatment stops. It may also indicate early heart disease and obesity.
research Evaluation of Resistance Resources and Analysis of Resistance Mechanisms of Maize to Stalk Rot Caused by Fusarium Graminearum
Some maize lines resist stalk rot better due to specific genes and enzyme activities.
research Reconstruction of a Sideburn by a Rotated Flap
Doctors successfully rebuilt a sideburn using skin and hair from near the ear in one surgery.
research Modulating Aging and Aging-Related Symptoms Using Endogenous Small Molecules
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
research Melatonin and Hair Physiology: Reasons and Clinical Efficacy Data as Treatment
Melatonin applied to the scalp helps treat early-stage hair loss in men and women.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction and metabolism.
research The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles
Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
research A Rare Case of Acrodermatitis Enteropathica in a One-Year-Old Child
A one-year-old child with a genetic condition had symptoms improved by treating zinc deficiency.
research Observational Study of Hair Follicle Cultured in Williams E Medium In Vitro
Human scalp hair follicles grow well in Williams E medium, which may help with hair transplants.
research Alcohol and Prostate Cancer: Time to Draw Conclusions
Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
research A Tricky Case of Hair Loss in a Child: Trichoscopy Saves the Day
Trichoscopy helped diagnose and cure a child's hair loss caused by a fungal infection.