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Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

The document concludes that terbinafine is effective for treating scalp fungal infections in children and recommends not excluding them from school during treatment, while also highlighting the need for updated treatment guidelines due to changing infection patterns.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.

A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.

Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.

Compound 15a was effective in inhibiting 5α-reductase.

Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

The document concludes that accurate diagnosis of alopecia in children relies on thorough examination and history, and while treatments exist, none can alter the course of alopecia areata, which can significantly affect a child's psychological well-being.

Dermoscopy and trichoscopy are useful for diagnosing skin signs in Dermatomyositis.

A patient with Cronkhite-Canada Syndrome developed colon cancer that spread to the liver, showing the need for regular cancer checks in such patients.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

Alopecia in dogs is often caused by mange, flea and tick infestations, and nutritional deficiencies, especially in males and young dogs.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

A cross-bred lamb with severe skin and movement issues had ichthyosis fetalis but normal vitamin A levels.

The TRPV3 gene variant may cause the long-haired suri alpaca coat.

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

Lentiginous melanoma is most common on the face, especially the nose, cheek, and pre-auricular areas, with men more likely to have it on the scalp, ears, upper back, and trapezius, and women on the cheek and anterior arm. Sun damage is a key factor in its formation.

Maintaining anticoagulation is crucial for patients with antiphospholipid syndrome.

Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

The Janwal Pashmi dog is a medium-sized, mostly black breed with specific body measurements, and adult males are generally larger than females.

Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

Ultraviolet light treatment with trioxsalen was ineffective for vitiligo in the cases described.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.