240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.
196 citations
,
March 2016 in “Nature Communications” In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
73 citations
,
April 2010 in “Anais Brasileiros de Dermatologia” This study concluded that dermoscopy enhances the diagnostic capability for cicatricial alopecia beyond clinical inspection and identified novel dermoscopic features such as blue-grey dots.
64 citations
,
January 1998 in “Drugs” In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.
54 citations
,
October 2002 in “Journal of controlled release” This study found that increasing a drug's lipophilicity and adding ethanol to the donor phase can enhance its delivery to the hair follicle, although the precise transport mechanism remains unclear.
47 citations
,
January 2013 in “International Journal of Cosmetic Science” This review explores genetic and lifestyle factors influencing hair diversity and reports no new findings, calling attention to the potential for future discoveries in genetic and epigenetic research.
44 citations
,
April 2003 in “European journal of pharmaceutical sciences” This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.
29 citations
,
January 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that trichoscopic examination is useful for diagnosing and monitoring systemic lupus erythematosus, with severe diffuse non-scarring alopecia indicating active disease.
23 citations
,
November 2015 in “Phytotherapy Research” This study found that cucurbitacin I from bitter melon most effectively inhibited the growth of lung cancer cells and promoted hair cell growth in cell cultures.
22 citations
,
January 2013 in “International Journal of Trichology” Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.
20 citations
,
January 1990 in “Journal of dermatological treatment” This study found that both ketoconazole 2% shampoo and selenium sulphide are effective for dandruff treatment, but ketoconazole also reduces hair growth.
13 citations
,
August 2007 in “Journal of Investigative Dermatology” Mouse hair can regrow in a special lab setup without serum.
12 citations
,
September 2018 in “International Journal of Cosmetic Science” This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.
11 citations
,
May 2021 in “Asian Journal of Pharmaceutical and Clinical Research” This review summarizes the phytomedicinal importance of Eclipta alba in Ayurvedic and folk medicine, particularly its use for hair growth and various biological properties, without reporting new clinical results.
8 citations
,
May 2003 in “Clinical and Experimental Dermatology” This case report suggests that nonsynchronized segmented heterochromia in black scalp hair in a 14-year-old girl may represent premature greying unrelated to deficiencies in iron, copper, zinc, or protein.
7 citations
,
June 2020 in “Experimental dermatology” This study identified key lipid differences between black and white hair in individuals with premature greying, highlighting vitamin D3 as a potential target for further research in understanding this condition.
7 citations
,
January 2020 in “Nature” This study found that stress-induced signaling from the sympathetic nervous system in mice led to the depletion of stem cells in hair follicles, resulting in premature greying.
6 citations
,
March 2009 in “Pigment Cell & Melanoma Research” This study suggests that a purified sphingolipid fraction can activate melanocyte stem cells via p38 signalling, potentially offering a non-UV-based treatment for vitiligo, though additional validation is needed.
4 citations
,
May 2024 in “Experimental Dermatology” This study reviews the role of the KIT ligand and receptor pathway in managing melanocyte and mast cell-related skin diseases, examining how its regulation can lead to potential therapies for conditions like vitiligo, melanoma, and mastocytosis. Results are not reported.
4 citations
,
November 2022 in “Journal of biomedical materials research. Part B, Applied biomaterials” This study demonstrated that human hair keratins have strong antioxidative properties, providing protection against oxidative stress in human dermal fibroblasts, suggesting their potential as antioxidizing supplements.
3 citations
,
February 2022 in “Journal of Dermatological Science” This study identified clinical features and genetic variants associated with early onset female pattern hair loss, highlighting decreased hair shaft density and specific SNPs related to androgenic features.
2 citations
,
March 2023 in “Journal of Nepal Medical Association” This study found that 40.42% of undergraduate medical students aged under 25 had early canities, with grade I being the most common.
2 citations
,
October 2022 in “International journal of Ayurvedic medicine” This review examines the traditional uses and biological activities of Glycyrrhiza glabra in Ayurveda, but reports no new clinical results; the authors identify a gap in evidence supporting its medicinal potential.
2 citations
,
July 2022 in “Indian Journal of Dermatology Venereology and Leprology” This study found that patients with premature greying of hair had significant abnormalities in cardiovascular risk markers, including elevated IL-6 levels, compared to healthy controls.
2 citations
,
May 2011 in “Pigment Cell & Melanoma Research” In this study, Tanimura et al. reported that loss of collagen XVII in mice leads to hair loss and pigmentation defects, potentially due to impaired TGF-beta signaling affecting melanocyte stem cell maintenance.
2 citations
,
January 2005 in “PubMed” In this study, females with hirsutism showed higher levels of certain androgens and reported more frequent symptoms such as infertility and increased skin greasiness compared to those without hirsutism.
2 citations
,
June 1997 in “The American Journal of Cosmetic Surgery” This article discusses methods for camouflaging surgical sites after hair transplant procedures and presents no new clinical findings.
1 citations
,
May 2023 in “Research journal of pharmacognosy and phytochemistry” This article discusses the growing preference for organic and herbal cosmetics for hair care, attributing this trend to reduced side effects compared to their synthetic counterparts, and highlights ingredients like fenugreek, flaxseed, and ginger for their potential benefits in preventing hair issues and promoting growth.
1 citations
,
January 2023 in “AYUSHDHARA” This paper reviews the Ayurvedic formulation Nilibhringadi Taila, which is claimed to improve hair quality and treat issues such as split hairs, premature greying, and baldness, and emphasizes the need for further research on its uses and effectiveness.
1 citations
,
July 2021 in “Journal of Central South University. Medical sciences” This study investigates how exercise relates to the severity of androgenic alopecia and aims to guide patients in selecting appropriate exercise types and amounts, but reports no new clinical results.