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New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Men with urinary symptoms are more likely to have erectile dysfunction, and there's a debate about research methods and authorship ethics.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Surgical and chemical castration have varied effects on heart and brain inflammation and artery function in sick rats.

Women with PCOS have higher oxidative stress and hormone imbalances, suggesting managing oxidative stress could help.

Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.

Using high doses and multiple drugs with steroids is risky and should be prevented.

PCOS is the most common cause of hirsutism, and personalized treatment is important.

Both estrogens and androgens are important for health in both males and females.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.

The letter is skeptical about the effectiveness of anti-androgen therapy for COVID-19 and calls for strong evidence from clinical trials.

A postmenopausal woman's excess male hormone symptoms improved after her ovaries were removed.

Exosome treatment safely increases hair density in male patients with androgenetic alopecia.

Secondary amenorrhea has many causes and requires thorough evaluation to treat and restore menstrual cycles.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

New treatments for PCOS focus on managing symptoms and improving fertility.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

The document concludes that hair loss in women can be treated with topical treatments or hormone therapy depending on the cause.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

COVID-19 may harm male fertility and damage the reproductive system.