Precocious Puberty: Trends, Contributing Factors, and Treatment

    July 2015 in “ Pediatrics in review ”
    Dominique Long
    TLDR Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.
    Precocious puberty (PP) was defined as pubertal changes occurring before age 8 in girls and 9 in boys. Recent studies in the US and Europe confirmed a trend toward earlier puberty, linked to factors like obesity, endocrine-disrupting chemicals, and intrauterine growth restriction. A 1997 study by Herman-Giddens et al found breast development in 15% of African American girls and 5% of white girls at age 7, prompting new guidelines from the Lawson Wilkins Pediatric Endocrine Society. More recent data by Biro et al reported the onset of breast development at 8.8 years for African American, 9.3 years for Hispanic, and 9.7 years for both white non-Hispanic and Asian girls.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 63 results

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Ronaldo and his Brothers Hairline (10 years difference)

      in Chat  498 upvotes 5 months ago
      Ronaldo's hairline remains sharp, while his brother's is receding. Opinions vary on whether Ronaldo uses treatments like finasteride or has had hair transplants, with some attributing his hairline to genetics and others to possible medical interventions.

      community The celebrated doctors that we adore so much and whose advice we hear without doubts, are only humans after all

      in Finasteride/Dutasteride  2 upvotes 9 months ago
      The user visited three dermatologists for hair loss treatment and was disappointed with their lack of thorough examination and discussion. Treatments prescribed included minoxidil, finasteride, multivitamins, ketoconazole shampoo, vitamin D3, and biotin, but the user was dissatisfied with the approach and lack of consideration for newer treatments.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 9 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community 4600 - result 9 month - Dr. Carman

      in Progress Pictures  253 upvotes 10 months ago
      A user shared their 9-month post-hair transplant results with 4600 grafts, using only Nourkin hair vitamins, Vitamin D, and B12, and expressed satisfaction. The replies debated the necessity of medications like finasteride and minoxidil for maintaining hair health.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  122 upvotes 1 year ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

    Similar Research

    5 / 730 results
      Polycystic Ovary Syndrome: Etiology, Pathogenesis, and Diagnosis

      research Polycystic Ovary Syndrome: Etiology, Pathogenesis, and Diagnosis

      991 citations, January 2011 in “Nature Reviews Endocrinology”
      The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
      Acne

      research Acne

      2 citations, May 2011 in “Harper's Textbook of Pediatric Dermatology”
      Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
      Acne Protection: Measures and Miseries

      research Acne Protection: Measures and Miseries

      January 2019 in “ARC journal of pharmaceutical sciences”
      Acne can be managed with various treatments and requires psychological support due to its emotional impact.