47 citations,
May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
46 citations,
September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
46 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
46 citations,
January 2008 in “Climacteric” Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
46 citations,
October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.
45 citations,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
44 citations,
April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.
43 citations,
July 2018 in “Journal of The European Academy of Dermatology and Venereology” Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.
42 citations,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
42 citations,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
40 citations,
April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
40 citations,
March 2016 in “The Journal of Clinical Endocrinology & Metabolism” Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.
40 citations,
December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
40 citations,
January 2003 in “Gynecological Endocrinology” Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.
40 citations,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.
40 citations,
May 1987 in “The Lancet” Minoxidil helps some bald men, but most lose hair again when stopping.
40 citations,
March 1982 in “British Journal of Dermatology” Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
39 citations,
May 2014 in “Frontiers in Pharmacology” Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
38 citations,
January 2011 in “Endocrine Journal” Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
38 citations,
December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
38 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
38 citations,
July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
37 citations,
September 2018 in “Psychoneuroendocrinology” Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
36 citations,
May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
36 citations,
October 2016 in “Bone” A male with aromatase deficiency improved bone health with estradiol treatment.
35 citations,
April 2013 in “Sexual medicine reviews” 5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
35 citations,
February 2012 in “The New England Journal of Medicine” Early diagnosis and treatment of TPP can prevent complications.
34 citations,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
34 citations,
June 2010 in “Archives of Disease in Childhood” Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.
33 citations,
April 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.