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Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

DHT may increase the risk of heart disease and death in elderly men.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Finasteride may cause slight depression and anxiety.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Prolactin affects when mice shed and grow hair.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Diane 35 plus finasteride is more effective for treating hirsutism.