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A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

The dog's skin condition improved after removing a tumor that was causing hormone imbalances.

A woman's masculine symptoms were caused by a rare tumor in her left ovary, which was found using a special blood test.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Hair loss in postmenopausal woman caused by ovarian issue.

A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Hormones control reproduction and are crucial for body balance.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Myrtle has various health benefits and potential for medicine development.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Stem cell niches are adaptable and key for tissue maintenance and repair.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.