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Glossary Testis

organ producing sperm and testosterone in male mammals

The testis, also known as the testicle or male gonad, is an organ found in male mammals that produces sperm and testosterone, the primary male sex hormone. Located in the scrotum, the testes play a crucial role in male fertility and secondary sexual characteristics, such as muscle mass and body hair growth.

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Research

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research Characteristics of flutamide action on prostatic and testicular functions in the rat

30 citations , June 1988 in “Journal of Steroid Biochemistry”

This study found that combining Flutamide and an LHRH agonist in adult male rats effectively inhibited prostatic growth and reduced androgen-sensitive prostatic activity markers to levels similar to castrated rats.

research Association between testicular microlithiasis and primary malignancy of the testis: our experience and review of the literature

22 citations , June 2007 in “Radiologia Medica”

Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.

research Curcumin derivatives inhibit testicular 17β-hydroxysteroid dehydrogenase 3

19 citations , March 2010 in “Bioorganic & Medicinal Chemistry Letters”

This study evaluated curcumin analogues as potential inhibitors of 17β-HSD3 in rat and human models, but it does not report new clinical findings.

research Testicular Seminoma in a Transgender Woman: A Case Report

16 citations , January 2019 in “LGBT health”

Transgender women can still get testicular cancer, so proper screening is important.

research Baldness and testicular cancer: the EPSAM case-control study

6 citations , January 2016 in “International Journal of Andrology”

In this study, researchers found an inverse association between baldness and testicular cancer, suggesting androgen activity may influence cancer risk.

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Community Join

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community Testosterone increased after six months of finasteride

12 upvotes 3 months ago

A 23-year-old male experienced an increase in testosterone levels after taking 1 mg of finasteride daily for six months, with no significant side effects reported. Users discussed how finasteride inhibits DHT, leading to increased testosterone, and debated the psychological versus physiological effects of the medication.

community Testicular ultrasound is it necessary to do?

4 months ago

A 25-year-old male experienced increased testosterone and estradiol levels after starting finasteride for hair loss, leading his doctor to suggest a testicular ultrasound as a precaution. The user questions the necessity of the ultrasound, considering it potentially excessive, while others suggest it could be a useful precaution to rule out any issues.

community Can testosterone alone cause hair loss even after nuking DHT?

in Research/Science 26 upvotes 7 months ago

Testosterone can still cause hair loss even when DHT is blocked by dutasteride, especially if hair follicles are sensitive. Topical treatments like RU58841 or pyrilutamide may help, but their long-term effectiveness is uncertain compared to dutasteride.

community Testing recommendations from lack of min/fin success

1 upvotes 8 months ago

The user has been using minoxidil, finasteride, a laser cap, and ketoconazole shampoo for hair loss without success and is seeking advice on further tests or treatments. They have a family history of hair loss and have not yet undergone dermatologist or trichology tests.

community Testosterone and Estradiol levels on 1 mg/day dutasteride

43 upvotes 11 months ago

A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015.

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Learn

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learn Bicalutamide

Could bicalutamide help trans women regrow hair lost to testosterone? No study has tested bicalutamide for hair regrowth in trans women. In cisgender women the only randomized trial found it added nothing to minoxidil, and it is an off-label prescription drug that requires liver monitoring.

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