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Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

SHBG may be a useful early indicator and treatment target for PCOS.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Certain drugs that block specific enzymes can help treat prostate diseases.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.