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Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.

The conclusion is that more research is needed to understand if the drug finasteride causes Post-Finasteride Syndrome or if it's due to individual genetic makeup.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Amenorrhea, or missing periods, is caused by various factors and is treated based on the specific cause.

Accurate assessment of puberty using Tanner staging is crucial for identifying normal and abnormal development.

Darker skin in 10-year-old girls may be an early sign of puberty.

Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.

Serenoa repens (saw palmetto) may cause side effects like hot flashes in children and needs more research for safety in pediatric use.

A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.

Bicalutamide may help treat female pattern hair loss.

ADAM17 could be a potential target for treating PCOS.

The research found that certain microRNAs are important for human hair growth and health.